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Om 22 to 56 h [8, 20, 21, 32?4]. A higher degree of glycosylation on the rhC1-INH protein results in faster clearance of rhC1-INH from the circulation compared with human plasma-derived C1-INH protein [32]. The pharmacokinetic profile of rhC1-INH was similar after single and multiple dosing [32]. The final estimation of the volume of distribution was 2.9 L, which is consistent with the reported vo

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