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Ng that free plasmin is rapidly inhibited by the plasma component 2-antiplasmin (13). In addition, no cleavage of HK was observed when plasminogen-deficient plasma was incubated with pSK for up to 240 min (Fig. 3B). We further incubated plasma with bacterial supernatants. Purified SK and kaolin were used as positive controls (Fig. 3C). Incubation of normal plasma with M49 wild-type supernatant, pS

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